Deaths from liver disease are increasing in England. This is in contrast to most EU countries where liver disease deaths are falling. In 2014 the number of people who died with an underlying cause of liver disease in England rose to 11,597. This rise is in contrast to other major causes of disease which have been declining. Liver disease is largely preventable. Whilst approximately 5% is attributable to autoimmune disorders (diseases characterised by abnormal functioning of the immune system), most liver disease is due to three main risk factors: alcohol, obesity and viral hepatitis.